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視網膜再生 日本啟動研究
Aug 15th 2013, 01:25

位於神戶市的日本理化學研究所與尖端醫療中心醫院,已針對「誘導性多功能幹細胞」(iPS)再生視網膜的臨床研究徵求患者,代表全球iPS臨床研究的正式啟動。

徵求的對象是「增齡性黃斑病變」患者,這是一種視網膜受傷導致視力急劇下降,甚至失明的頑疾,日本國內約有70萬這類患者。具體條件為50歲以上、矯正視力不足0.3、治療藥物無效、視野中心部分較暗等。

臨床研究中,科研人員將利用自患者手腕採集的皮膚組織製成iPS細胞,再將之轉化成視網膜色素上皮細胞,並製成薄膜狀,最後移植至患部。此項研究若成功,將可有效解決器官捐贈不足的問題。

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